IMG_4279

Otilia Nuta, PhD


Department: Biology
Position: Assistant Professor
Degree:
Office: 7e.539
Email: otilia.nuta@nu.edu.kz
Phone:

After finishing her Degree in Theoretical Physics at “Al.I.Cuza” University of Iasi, Romania
Otilia obtained a fellowship for a postgraduate course in Medical Physics at University of
Patras, Greece. This was followed by an MSc in Radiation Biology at University College
London, UK and a PhD in Radiation Biology at Dublin Institute of Technology, Ireland, both
funded by the EU. The PhD dissertation has been developed at three sites: DIT in Ireland,
LUMC in the Netherlands and the Gray Cancer Institute in the UK.
She then went to do a Post-doctoral in the Public Health England in Harwell, UK where she
investigated the impact of long-term exposure to low concentrations of chemicals on the cellular
response to ionising radiation through the use of in vitro cytogenetics. During this appointment
she also participated in other substantial team projects:

  • INSIGHT-aiming at identifying early cell and molecular processes modulating late normal
    tissue responses to radiotherapy for breast cancer (collaboration with Royal Marsden
    Hospital, UK and Mannheim Medical Center, Germany)
  • Bio-dosimetry for synchrotron microbeam radiation therapy (collaboration with European
    Synchrotron Radiation facility, Grenoble, France)

Dr. Nuta has several years of experience in teaching MSc courses in the Radiation Biology
programme and the Cancer programme at University College London.
From there she moved to KFSH&RC in Riyadh, Saudi Arabia to do training in HDR
Brachytherapy treatment planning for patients with gynecological cancers.
In 2014 Otilia joined Pavia University, Italy as postdoctoral fellow to work as part of the
EUTEMPE-RX project (funded by Horizon 2020) on the development of the online
Radiation Biology teaching module for European Board-based expert level accreditation in
Medical Physics Experts in Radiology and Interventional Radiology.
In 2016 she joined NUSOM; during her appointment she developed educational teaching
and learning materials for courses of MD, Master of Public Health, and Master in Molecular
Medicine programmes and she co-Directed the Master in Molecular Medicine programme.

During all this time she guided numerous students or visiting scientists.


RESEARCH INTERESTS

  • Biological dosimetry for radiations and chemicals
  • Targeted radiotherapy as a powerful method to bring radiation dose directly to the critical
    cancer cells and thus improve treatment results of advanced stages of cancers, in particular
    metastatic disease
  • Carcinogenesis
  • Non-targeted radiation effects

SELECTED PUBLICATIONS

  • Correlation between the radiation responses of fibroblasts cultured from individual patients
    and the risk of late reaction after breast radiotherapy. [Cancer Letters; doi:
    10.1016/j.canlet.2016.02.036]
  •  Correlation between DNA damage responses of skin to a test dose of radiation and late
    adverse effects of earlier breast radiotherapy. [Radiotherapy and Oncology; doi:
    10.1016/j.radonc.2016.04.012]
  • Impact of long term exposure to sodium arsenite on cytogenetic radiation damage.
    [Mutagenesis 2014; doi: 10.1093/mutage/get070]
  • The impact of the bystander effect on the low-dose hypersensitivity phenomenon.
    [Radiation and Environmental Biophysics 2008, 47[2]:265-74]
  • Energy Deposition by Alpha Particles [2keV- 1 MeV] in cylindrical targets. [MRC Monograph
    2002/1 | 220 Pages]